PT -期刊文章盟Gregory王盟-布莱恩Yoo盟- Reza贾汗AU -维克多Szeder AU -大卫Liebeskind盟Latisha Sharma AU -加里Duckwiler盟Satoshi Tateshima AU -努尔盟——克里斯蒂娜Shkirkova AU - Jin-Moo李盟-西德尼·斯达克曼AU -杰弗里节省TI -频率,决定因素,和结果相关的远端栓子机械血栓切除术对急性缺血性中风(S21.003) DP - 2018年4月10 TA -神经病学PG - S21.003 VI - 90 IP - 15补充4099 - //www.ez-admanager.com/content/90/15_Supplement/S21.003.short 4100 - //www.ez-admanager.com/content/90/15_Supplement/S21.003.full所以Neurology2018 首页4月10;90 AB -目的:我们试图理解的频率,决定因素,结果患者远端栓子(DE)进一步了解急性缺血性中风的病理生理学。背景:血栓碎片和远端栓塞是担心机械血栓切除术的并发症急性缺血性中风,但频率,决定因素,结果与现代血管内再灌注技术差的特点。梯度回波(GRE)核磁共振,重新执行之前和之后的干预,是一种新型技术直接可视化DE和描述他们的原因和后果。设计/方法:我们分析了连续急性缺血性中风血栓切除术患者MR成像预处理和干预。德被定义为新的GRE船需要术后易感性的迹象,在动脉远端在新界目标遮挡或。结果:在连续50例,年龄为70.4(±15.8),44%的是女性,署15(差8-19)。血栓切除术技术包括猎犬独自在42%,愿望只有8%,寻回犬和愿望50%,其他(如血管成形术、线浸渍)22%。实质性的速度再灌注(mTICI 2酮)为84%。新德下游目标遮挡的领土被发现在22%的患者(91%,9%)的多个单,虽然没有栓子观测到一个新的领域。与IV tPA预测DE:预处理(出现在64%的患者DE vs 26%, p = 0.03);和ICA闭塞目标位置(64%比28%,p = 0.04)。 Nominal differences in the 3-month rate of severely disabled or dead outcome (mRS 5–6) did not reach statistical significance (44% vs 24%, p=0.40).Conclusions: In the modern neurothrombectomy era, distal emboli within the territory of the target occlusion occur in more than 1 in 5 patients, but embolization to new territories is very uncommon. Predictors of distal emboli are prior intravenous thrombolytic therapy (increasing clot friability) and ICA occlusion location (requiring manipulation of larger thrombi).Study Supported by:AAN Medical Student Summer Research ScholarshipWashington University School of Medicine Summer Research Program Dean’s Fellowship

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