% 0期刊文章%西蒙娜Lattanzi %一个Gabriele Pagliariccio卢西亚诺烧炭党人% %一个Bartolini马可%克劳迪娅Cagnetti %乔凡娜Viticchi %劳拉·布拉%莱安德罗Provinciali %毛罗·Silvestrini % T神经认知功能和颈动脉内膜切除手术后脑血管反应性% D R 10.1212 / WNL 2018%。0000000000004862 % J首页神经病学% P e307-e315 % V 90% N 4% X客观评价TIA患者和同侧颈内动脉(ICA)高档狭窄是否认知能力和脑血流动力学的变化发生在颈动脉内膜切除术(CEA)并探讨他们之间的关系。方法受试者接受CEA的病人,TIA在过去6个月,有一个侧ICA狭窄严重。彩色推理(CPM) +复杂图复制测试(CFCT)和语音(ph) +分类(ca)语言流畅(VF)测试进行评估右和左半球认知功能,分别。与经颅多普勒超声血流动力学评估通过大脑血管舒缩反应(表格)血碳酸过多症。结果共有137名患者被包括在内。东航之前,患者对ICA获得较低的分数在CPM和CFCT;离开了ICA狭窄患者语音和直言VF测试表现比较差的。表格是下降的狭窄。在6个月从东航,表格和认知能力显著提高。在认知测试中的性能变化探索将近半球侧表格变化呈正相关(CPM:线性回归R2 = 0.759, adjR2 = 0.737;CFCT: R2 = 0.734, adjR2 = 0.710;(ph) VF: R2 = 0.774, adjR2 = 0.749; (ca)VF: R2 = 0.732, adjR2 = 0.703).Conclusion Cognitive performance was enhanced at 6 months since CEA, and the improvement was related to the CVR increase. Cerebral hemodynamics may be an independent and potentially reversible determinant of cognitive dysfunction in severe carotid artery disease.BH=breath-holding; BHI=breath-holding index; ca=categorical; CEA=carotid endarterectomy; CFCT=Complex Figure Copy Test; CPM=Coloured Progressive Matrices; CVR=cerebral vasomotor reactivity; ICA=internal carotid artery; MFV=mean flow velocity; pCVR=preserved cerebral vasomotor reactivity; ph=phonemic; rCVR=reduced cerebral vasomotor reactivity; VF=Verbal Fluency %U //www.ez-admanager.com/content/neurology/90/4/e307.full.pdf