@article {Zalewskie96作者={尼古拉斯·l·Zalewski Eoin p·弗拉纳根和b .马克Keegan}, title ={评价特发性横向脊髓炎揭示特定脊髓病诊断},体积={90}={2},页面= {e96——e102} = {2018}, doi = {10.1212 / WNL。出版商0000000000004796}= {Wolters Kluwer健康,公司代表美国神经病学学会},文摘={目的评估特定脊髓病诊断疑似特发性患者制造横向脊髓炎(ITM)。首页方法226例18岁及以上被称为梅奥诊所的神经因涉嫌ITM从12月1日,2010年,2015年12月31日。首页综述了电子医疗记录详细的临床表现和课程,实验室和电生理学的调查和神经影像学确定病因。目前的ITM和替代脊髓病诊断标准诊断应用。所有情况下差异被怀疑从最终报告每个作者综述了临床诊断的诊断,最终达成共识。结果诊断标准ITM遇到226年41例(18.1 \ %)。在158名患者(69.9 \ %),另一种特定的脊髓病的诊断是:多发性硬化症或临床孤立综合征,75;血管脊髓病,41岁;神经,12;视neuromyelitis谱系障碍,12;髓鞘少突细胞糖蛋白脊髓病,5;肿瘤4; compressive, 3; nutritional, 3; infectious, 2; and other, 2. A myelopathy was not confirmed in 27 patients. Time from symptom onset to final clinical diagnosis in patients without ITM was a median of 9 months (range 0{\textendash}288). Fifty-five patients (24\%) required treatment changes according to their final clinical diagnosis.Conclusions The majority of patients with suspected ITM have an alternative specific myelopathy diagnosis. A presumptive diagnosis of ITM can lead to premature diagnostic conclusions affecting patient treatment.ACE=angiotensin-converting enzyme; ADEM=acute disseminated encephalomyelitis; AQP4=aquaporin-4; ASIA=American Spinal Injury Association; CIS=clinically isolated syndrome of demyelination; DAVF=dural arteriovenous fistula; EDSS=Expanded Disability Status Scale; IgG=immunoglobulin G; ITM=idiopathic transverse myelitis; MOG=myelin oligodendrocyte glycoprotein; MS=multiple sclerosis; NMOSD=neuromyelitis optica spectrum disorders; PPMS=primary progressive multiple sclerosis; QREADS=Quick Query Radiographs and Photographs Electronic Analysis and Display Station; RRMS=relapsing-remitting multiple sclerosis; SCI=spinal cord infarction; TE=echo time; TR=repetition time; VGCC=voltage-gated calcium channel; VZV=varicella-zoster virus}, issn = {0028-3878}, URL = {//www.ez-admanager.com/content/90/2/e96}, eprint = {//www.ez-admanager.com/content/90/2/e96.full.pdf}, journal = {Neurology} }
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