Excitability out of balance
Treating hemineglect with transcranial magnetic brain stimulation
Citation Manager Formats
Make Comment
See Comments
This article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article can also be purchased.
Rehabilitation of hemineglect is vexingly inadequate. Beyond its direct detrimental effect on visual-spatial function, hemineglect interferes with rehabilitation of cognitive and motor function.1 Interventions targeting this condition include relearning appropriate visuospatial scanning behaviors through practice and cuing, engaging the attentional system with exogenous sensory stimulation, and changing excitability at the level of the brain.2 This last approach is based on Kinsbourne's3 theory of hemispheric rivalry, which posits that contralateral attention is subserved by each hemisphere, and mutual transcallosal inhibition checks overactivity in the opposite hemisphere to keep attention evenly distributed. Unilateral stroke is thought to disrupt this balance by reducing inhibition from the lesioned hemisphere to the contralesional hemisphere, resulting in greater overactivity in the contralesional hemisphere which in turn increases inhibition to the lesioned hemisphere; the end result is an asymmetric attentional field manifested as hemineglect. Changing cortical excitability by noninvasive brain stimulation is an emerging approach that aims to restore the functional balance, by either increasing activity in the lesioned hemisphere or suppressing overactivity in the contralesional hemisphere. Repetitive transcranial magnetic stimulation (rTMS) has been recognized as a …
AAN Members
We have changed the login procedure to improve access between AAN.com and the Neurology journals. If you are experiencing issues, please log out of AAN.com and clear history and cookies. (For instructions by browser, please click the instruction pages below). After clearing, choose preferred Journal and select login for AAN Members. You will be redirected to a login page where you can log in with your AAN ID number and password. When you are returned to the Journal, your name should appear at the top right of the page.
AAN Non-Member Subscribers
Purchase access
For assistance, please contact:
AAN Members (800) 879-1960 or (612) 928-6000 (International)
Non-AAN Member subscribers (800) 638-3030 or (301) 223-2300 option 3, select 1 (international)
Sign Up
Information on how to subscribe to Neurology and Neurology: Clinical Practice can be found here
Purchase
Individual access to articles is available through the Add to Cart option on the article page. Access for 1 day (from the computer you are currently using) is US$ 39.00. Pay-per-view content is for the use of the payee only, and content may not be further distributed by print or electronic means. The payee may view, download, and/or print the article for his/her personal, scholarly, research, and educational use. Distributing copies (electronic or otherwise) of the article is not allowed.
Letters: Rapid online correspondence
REQUIREMENTS
You must ensure that your Disclosures have been updated within the previous six months. Please go to our Submission Site to add or update your Disclosure information.
Your co-authors must send a completed Publishing Agreement Form to Neurology Staff (not necessary for the lead/corresponding author as the form below will suffice) before you upload your comment.
If you are responding to a comment that was written about an article you originally authored:
You (and co-authors) do not need to fill out forms or check disclosures as author forms are still valid
and apply to letter.
Submission specifications:
- Submissions must be < 200 words with < 5 references. Reference 1 must be the article on which you are commenting.
- Submissions should not have more than 5 authors. (Exception: original author replies can include all original authors of the article)
- Submit only on articles published within 6 months of issue date.
- Do not be redundant. Read any comments already posted on the article prior to submission.
- Submitted comments are subject to editing and editor review prior to posting.
You May Also be Interested in
Dr. Jessica Ailani and Dr. Ailna Masters-Israilov
► Watch
Related Articles
Alert Me
Recommended articles
-
Articles
Theta-burst stimulation of the left hemisphere accelerates recovery of hemispatial neglectG. Koch, S. Bonnì, V. Giacobbe et al.Neurology, December 14, 2011 -
Five New Things
NeurorehabilitationFive new thingsA.M. Barrett, Mooyeon Oh-Park, Peii Chen et al.Neurology: Clinical Practice, November 13, 2013 -
Articles
Dissociation of neglect subtypes with transcranial magnetic stimulationG. A. Ghacibeh, J. I. Shenker, K. H. Winter et al.Neurology, September 10, 2007 -
Articles
Functional anatomy of the therapeutic effects of prism adaptation on left neglectJ. Luauté, C. Michel, G. Rode et al.Neurology, June 26, 2006