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To the Editor:
We read with interest the article by Ainiala et al.1 describing the prevalence of neuropsychiatric syndromes in SLE. Neuropsychiatric syndromes may be present in patients with SLE (more than 50%), not only through serious manifestations such as seizures and psychosis but in other more subtle ways, such as cognitive impairment and mood disorder, even in neurologically or psychiatrically asymptomatic patients.2,3⇓ In this study, only 14 of 37 patients (38%) tested with cognitive dysfunction had cognitive problems. We studied 15 women with SLE in a control group with a mean age of 27.8 ± 6.35 years, mean disease duration since diagnosis of SLE of 4.8 ± 3.5 years, and mean level of education of 11.7 ± 6.3 years.4 At the time of the study, all patients were receiving low doses …
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