2022年3月8日
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协会的时机开始和西洛地唑双重抗血小板治疗复发性中风
一个CSPS.com试验事后分析
第一次出版2022年1月24日,
DOI: https://doi.org/10.1212/WNL.0000000000200064
其它丰田章男
部门的脑血管药(K.T.、k Miwa表示抗议,T.Y.), Data Science (K.O.), and Neurology (M.I.), National Cerebral and Cardiovascular Center, Suita; Department of Neurology (H.H.), Tokyo Saiseikai Central Hospital; Clinical Research Center for Medicine (S.U.), International University of Health and Welfare, Center for Brain and Cerebral Vessels, Sanno Medical Center; Department of Neurological Science (K.K.), Graduate School of Medicine, Nippon Medical School, Tokyo; Headquarters of the Iseikai Medical Corporation (K. Minematsu), Osaka; Department of Neurology (K.Y.), Ichinomiya Nishi Hospital; Department of Neurosurgery (Y.S.), Yuri Kumiai General Hospital, Yurihonjo; Department of Neurology (S.T.), Nitobe Memorial Nakano General Hospital; and Department of Neurology (K.K.), Tokyo Women's Medical University, Japan.
大友Omae
部门的脑血管药(K.T.、k Miwa表示抗议,T.Y.), Data Science (K.O.), and Neurology (M.I.), National Cerebral and Cardiovascular Center, Suita; Department of Neurology (H.H.), Tokyo Saiseikai Central Hospital; Clinical Research Center for Medicine (S.U.), International University of Health and Welfare, Center for Brain and Cerebral Vessels, Sanno Medical Center; Department of Neurological Science (K.K.), Graduate School of Medicine, Nippon Medical School, Tokyo; Headquarters of the Iseikai Medical Corporation (K. Minematsu), Osaka; Department of Neurology (K.Y.), Ichinomiya Nishi Hospital; Department of Neurosurgery (Y.S.), Yuri Kumiai General Hospital, Yurihonjo; Department of Neurology (S.T.), Nitobe Memorial Nakano General Hospital; and Department of Neurology (K.K.), Tokyo Women's Medical University, Japan.
Haruhiko Hoshino
部门的脑血管药(K.T.、k Miwa表示抗议,T.Y.), Data Science (K.O.), and Neurology (M.I.), National Cerebral and Cardiovascular Center, Suita; Department of Neurology (H.H.), Tokyo Saiseikai Central Hospital; Clinical Research Center for Medicine (S.U.), International University of Health and Welfare, Center for Brain and Cerebral Vessels, Sanno Medical Center; Department of Neurological Science (K.K.), Graduate School of Medicine, Nippon Medical School, Tokyo; Headquarters of the Iseikai Medical Corporation (K. Minematsu), Osaka; Department of Neurology (K.Y.), Ichinomiya Nishi Hospital; Department of Neurosurgery (Y.S.), Yuri Kumiai General Hospital, Yurihonjo; Department of Neurology (S.T.), Nitobe Memorial Nakano General Hospital; and Department of Neurology (K.K.), Tokyo Women's Medical University, Japan.
Shinichiro中山教授
部门的脑血管药(K.T.、k Miwa表示抗议,T.Y.), Data Science (K.O.), and Neurology (M.I.), National Cerebral and Cardiovascular Center, Suita; Department of Neurology (H.H.), Tokyo Saiseikai Central Hospital; Clinical Research Center for Medicine (S.U.), International University of Health and Welfare, Center for Brain and Cerebral Vessels, Sanno Medical Center; Department of Neurological Science (K.K.), Graduate School of Medicine, Nippon Medical School, Tokyo; Headquarters of the Iseikai Medical Corporation (K. Minematsu), Osaka; Department of Neurology (K.Y.), Ichinomiya Nishi Hospital; Department of Neurosurgery (Y.S.), Yuri Kumiai General Hospital, Yurihonjo; Department of Neurology (S.T.), Nitobe Memorial Nakano General Hospital; and Department of Neurology (K.K.), Tokyo Women's Medical University, Japan.
克美木村
部门的脑血管药(K.T.、k Miwa表示抗议,T.Y.), Data Science (K.O.), and Neurology (M.I.), National Cerebral and Cardiovascular Center, Suita; Department of Neurology (H.H.), Tokyo Saiseikai Central Hospital; Clinical Research Center for Medicine (S.U.), International University of Health and Welfare, Center for Brain and Cerebral Vessels, Sanno Medical Center; Department of Neurological Science (K.K.), Graduate School of Medicine, Nippon Medical School, Tokyo; Headquarters of the Iseikai Medical Corporation (K. Minematsu), Osaka; Department of Neurology (K.Y.), Ichinomiya Nishi Hospital; Department of Neurosurgery (Y.S.), Yuri Kumiai General Hospital, Yurihonjo; Department of Neurology (S.T.), Nitobe Memorial Nakano General Hospital; and Department of Neurology (K.K.), Tokyo Women's Medical University, Japan.
薰古板的
部门的脑血管药(K.T.、k Miwa表示抗议,T.Y.), Data Science (K.O.), and Neurology (M.I.), National Cerebral and Cardiovascular Center, Suita; Department of Neurology (H.H.), Tokyo Saiseikai Central Hospital; Clinical Research Center for Medicine (S.U.), International University of Health and Welfare, Center for Brain and Cerebral Vessels, Sanno Medical Center; Department of Neurological Science (K.K.), Graduate School of Medicine, Nippon Medical School, Tokyo; Headquarters of the Iseikai Medical Corporation (K. Minematsu), Osaka; Department of Neurology (K.Y.), Ichinomiya Nishi Hospital; Department of Neurosurgery (Y.S.), Yuri Kumiai General Hospital, Yurihonjo; Department of Neurology (S.T.), Nitobe Memorial Nakano General Hospital; and Department of Neurology (K.K.), Tokyo Women's Medical University, Japan.
Kazuo Minematsu
部门的脑血管药(K.T.、k Miwa表示抗议,T.Y.), Data Science (K.O.), and Neurology (M.I.), National Cerebral and Cardiovascular Center, Suita; Department of Neurology (H.H.), Tokyo Saiseikai Central Hospital; Clinical Research Center for Medicine (S.U.), International University of Health and Welfare, Center for Brain and Cerebral Vessels, Sanno Medical Center; Department of Neurological Science (K.K.), Graduate School of Medicine, Nippon Medical School, Tokyo; Headquarters of the Iseikai Medical Corporation (K. Minematsu), Osaka; Department of Neurology (K.Y.), Ichinomiya Nishi Hospital; Department of Neurosurgery (Y.S.), Yuri Kumiai General Hospital, Yurihonjo; Department of Neurology (S.T.), Nitobe Memorial Nakano General Hospital; and Department of Neurology (K.K.), Tokyo Women's Medical University, Japan.
凯基山口
部门的脑血管药(K.T.、k Miwa表示抗议,T.Y.), Data Science (K.O.), and Neurology (M.I.), National Cerebral and Cardiovascular Center, Suita; Department of Neurology (H.H.), Tokyo Saiseikai Central Hospital; Clinical Research Center for Medicine (S.U.), International University of Health and Welfare, Center for Brain and Cerebral Vessels, Sanno Medical Center; Department of Neurological Science (K.K.), Graduate School of Medicine, Nippon Medical School, Tokyo; Headquarters of the Iseikai Medical Corporation (K. Minematsu), Osaka; Department of Neurology (K.Y.), Ichinomiya Nishi Hospital; Department of Neurosurgery (Y.S.), Yuri Kumiai General Hospital, Yurihonjo; Department of Neurology (S.T.), Nitobe Memorial Nakano General Hospital; and Department of Neurology (K.K.), Tokyo Women's Medical University, Japan.
Yoshitaka须
部门的脑血管药(K.T.、k Miwa表示抗议,T.Y.), Data Science (K.O.), and Neurology (M.I.), National Cerebral and Cardiovascular Center, Suita; Department of Neurology (H.H.), Tokyo Saiseikai Central Hospital; Clinical Research Center for Medicine (S.U.), International University of Health and Welfare, Center for Brain and Cerebral Vessels, Sanno Medical Center; Department of Neurological Science (K.K.), Graduate School of Medicine, Nippon Medical School, Tokyo; Headquarters of the Iseikai Medical Corporation (K. Minematsu), Osaka; Department of Neurology (K.Y.), Ichinomiya Nishi Hospital; Department of Neurosurgery (Y.S.), Yuri Kumiai General Hospital, Yurihonjo; Department of Neurology (S.T.), Nitobe Memorial Nakano General Hospital; and Department of Neurology (K.K.), Tokyo Women's Medical University, Japan.
Shuta Toru
部门的脑血管药(K.T.、k Miwa表示抗议,T.Y.), Data Science (K.O.), and Neurology (M.I.), National Cerebral and Cardiovascular Center, Suita; Department of Neurology (H.H.), Tokyo Saiseikai Central Hospital; Clinical Research Center for Medicine (S.U.), International University of Health and Welfare, Center for Brain and Cerebral Vessels, Sanno Medical Center; Department of Neurological Science (K.K.), Graduate School of Medicine, Nippon Medical School, Tokyo; Headquarters of the Iseikai Medical Corporation (K. Minematsu), Osaka; Department of Neurology (K.Y.), Ichinomiya Nishi Hospital; Department of Neurosurgery (Y.S.), Yuri Kumiai General Hospital, Yurihonjo; Department of Neurology (S.T.), Nitobe Memorial Nakano General Hospital; and Department of Neurology (K.K.), Tokyo Women's Medical University, Japan.
北侧一雄
部门的脑血管药(K.T.、k Miwa表示抗议,T.Y.), Data Science (K.O.), and Neurology (M.I.), National Cerebral and Cardiovascular Center, Suita; Department of Neurology (H.H.), Tokyo Saiseikai Central Hospital; Clinical Research Center for Medicine (S.U.), International University of Health and Welfare, Center for Brain and Cerebral Vessels, Sanno Medical Center; Department of Neurological Science (K.K.), Graduate School of Medicine, Nippon Medical School, Tokyo; Headquarters of the Iseikai Medical Corporation (K. Minematsu), Osaka; Department of Neurology (K.Y.), Ichinomiya Nishi Hospital; Department of Neurosurgery (Y.S.), Yuri Kumiai General Hospital, Yurihonjo; Department of Neurology (S.T.), Nitobe Memorial Nakano General Hospital; and Department of Neurology (K.K.), Tokyo Women's Medical University, Japan.
正文Ihara
部门的脑血管药(K.T.、k Miwa表示抗议,T.Y.), Data Science (K.O.), and Neurology (M.I.), National Cerebral and Cardiovascular Center, Suita; Department of Neurology (H.H.), Tokyo Saiseikai Central Hospital; Clinical Research Center for Medicine (S.U.), International University of Health and Welfare, Center for Brain and Cerebral Vessels, Sanno Medical Center; Department of Neurological Science (K.K.), Graduate School of Medicine, Nippon Medical School, Tokyo; Headquarters of the Iseikai Medical Corporation (K. Minematsu), Osaka; Department of Neurology (K.Y.), Ichinomiya Nishi Hospital; Department of Neurosurgery (Y.S.), Yuri Kumiai General Hospital, Yurihonjo; Department of Neurology (S.T.), Nitobe Memorial Nakano General Hospital; and Department of Neurology (K.K.), Tokyo Women's Medical University, Japan.
雅俊郎
部门的脑血管药(K.T.、k Miwa表示抗议,T.Y.), Data Science (K.O.), and Neurology (M.I.), National Cerebral and Cardiovascular Center, Suita; Department of Neurology (H.H.), Tokyo Saiseikai Central Hospital; Clinical Research Center for Medicine (S.U.), International University of Health and Welfare, Center for Brain and Cerebral Vessels, Sanno Medical Center; Department of Neurological Science (K.K.), Graduate School of Medicine, Nippon Medical School, Tokyo; Headquarters of the Iseikai Medical Corporation (K. Minematsu), Osaka; Department of Neurology (K.Y.), Ichinomiya Nishi Hospital; Department of Neurosurgery (Y.S.), Yuri Kumiai General Hospital, Yurihonjo; Department of Neurology (S.T.), Nitobe Memorial Nakano General Hospital; and Department of Neurology (K.K.), Tokyo Women's Medical University, Japan.
Takenori山口
部门的脑血管药(K.T.、k Miwa表示抗议,T.Y.), Data Science (K.O.), and Neurology (M.I.), National Cerebral and Cardiovascular Center, Suita; Department of Neurology (H.H.), Tokyo Saiseikai Central Hospital; Clinical Research Center for Medicine (S.U.), International University of Health and Welfare, Center for Brain and Cerebral Vessels, Sanno Medical Center; Department of Neurological Science (K.K.), Graduate School of Medicine, Nippon Medical School, Tokyo; Headquarters of the Iseikai Medical Corporation (K. Minematsu), Osaka; Department of Neurology (K.Y.), Ichinomiya Nishi Hospital; Department of Neurosurgery (Y.S.), Yuri Kumiai General Hospital, Yurihonjo; Department of Neurology (S.T.), Nitobe Memorial Nakano General Hospital; and Department of Neurology (K.K.), Tokyo Women's Medical University, Japan.
部门的脑血管药(K.T.、k Miwa表示抗议,T.Y.), Data Science (K.O.), and Neurology (M.I.), National Cerebral and Cardiovascular Center, Suita; Department of Neurology (H.H.), Tokyo Saiseikai Central Hospital; Clinical Research Center for Medicine (S.U.), International University of Health and Welfare, Center for Brain and Cerebral Vessels, Sanno Medical Center; Department of Neurological Science (K.K.), Graduate School of Medicine, Nippon Medical School, Tokyo; Headquarters of the Iseikai Medical Corporation (K. Minematsu), Osaka; Department of Neurology (K.Y.), Ichinomiya Nishi Hospital; Department of Neurosurgery (Y.S.), Yuri Kumiai General Hospital, Yurihonjo; Department of Neurology (S.T.), Nitobe Memorial Nakano General Hospital; and Department of Neurology (K.K.), Tokyo Women's Medical University, Japan.
协会的时机开始和西洛地唑双重抗血小板治疗复发性中风
一个CSPS.com试验事后分析
其它丰田章男,大友Omae,Haruhiko星野,Shinichiro中山教授,克美木村,薰古板的,KazuoMinematsu,凯基山口那津男,Yoshitaka须,Shuta渡边,Kazuo北川,正文Ihara,正敏四郎,Takenori山口那津男,代表CSPS.com试验调查
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2022年3月,
98年
(10)
e983-e992;
DOI:10.1212 / WNL.0000000000200064
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文章数据和数据
数据
图2
kaplan meier分析时间第一个事件的主要功效的结果,定义为缺血性中风
(一)8 - 14天组。(B) 15-28天集团。组(C) 29 - 180天。组(D) 15 - 180天。
图3
在双重治疗缺血性中风的风险比单一疗法根据试验药物的起始时间
调整危险比和95%可信区间开始试验药物治疗的患者在X轴或晚的那一天。
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