%PDF-1.4 % 43 0 obj <> endobj 42 0 obj <>stream Acrobat Distiller 7.0 (Windows) 23th January 2018 2023-09-28T05:23:25-07:00 0-00-00T00:02:01+00:01 Arbortext Advanced Print Publisher 9.1.510/W Unicode 2023-09-28T05:23:25-07:00 application/pdf NEUROLOGY2017871384 396..396 uuid:75d2b9c4-deee-402a-8ef1-cda92171d9db uuid:e9e56f57-1dd1-11b2-0a00-9000f83e80ff endstream endobj 40 0 obj <> endobj 19 0 obj <> endobj 18 0 obj <>/ExtGState<>/Font<>/ProcSet[/PDF/Text]>>/Rotate 0/TrimBox[36 36 630 818.64]/Type/Page>> endobj 45 0 obj <>/ProcSet[/PDF/Text/ImageB/ImageC]/XObject<>>>/Type/Page>> endobj 49 0 obj [56 0 R 57 0 R 58 0 R 59 0 R] endobj 50 0 obj <>stream q 192 0 0 51 237 695 cm /Im0 Do Q BT /T1_0 1 Tf 12 0 0 12 236.50809 630.99994 Tm (DOI 10.1212/WNL.0000000000004992)Tj 7.749 1 Td (2018;90;396 )Tj /T1_1 1 Tf -4.47201 0 Td (Neurology\240)Tj /T1_2 1 Tf -8.79248 1.00001 Td (Upgoing thumb sign: A sensitive indicator of brain involvement)Tj ET BT /T1_2 1 Tf 12 0 0 12 201.50409 604 Tm (This information is current as of February 19, 2018)Tj ET 108 459 450 137 re 0 0 m S BT /T1_2 1 Tf 10 0 0 10 118 566.99997 Tm (Services)Tj 0 1 TD (Updated Information &)Tj ET BT /T1_0 1 Tf 10 0 0 10 441.72974 566.99997 Tm ( )Tj 0 0 1 rg -17.47297 0 Td (http://n.neurology.org/content/90/8/396.full)Tj 0 g T* (including high resolution figures, can be found at:)Tj ET BT /T1_2 1 Tf 10 0 0 10 118 544 Tm (References)Tj ET BT /T1_0 1 Tf 10 0 0 10 481.71951 533.99997 Tm ( )Tj 0 0 1 rg -21.47195 0 Td (http://n.neurology.org/content/90/8/396.full#ref-list-1)Tj 0 g T* (This article cites 1 articles, 1 of which you can access for free at: )Tj ET BT /T1_0 1 Tf 10 0 0 10 118 505.99997 Tm (\240 )Tj /T1_2 1 Tf T* (Permissions & Licensing)Tj ET BT /T1_0 1 Tf 10 0 0 10 524.7699 495.99994 Tm ( )Tj 0 0 1 rg -25.77699 0 Td (http://www.neurology.org/about/about_the_journal#permissions)Tj 0 g T* (its entirety can be found online at:)Tj 0 1.00001 TD (Information about reproducing this article in parts \(figures,tables\) o\ r in)Tj ET BT /T1_0 1 Tf 10 0 0 10 118 467.99997 Tm (\240 )Tj /T1_2 1 Tf 0 1 TD (Reprints)Tj ET BT /T1_0 1 Tf 10 0 0 10 441.4299 467.99997 Tm ( )Tj 0 0 1 rg -17.44299 0 Td (http://n.neurology.org/subscribers/advertise)Tj 0 g T* (Information about ordering reprints can be found online:)Tj ET 108 209 450 46 re 0 0 m S BT /T1_0 1 Tf 10 0 0 10 113 216.99994 Tm (rights reserved. 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