%PDF-1.4
%
65 0 obj
<>
endobj
67 0 obj
<>stream
Acrobat Distiller 7.0 (Windows)
21th July 2016
2023-11-26T11:45:51-08:00
0-00-00T20:16:00Z
Arbortext Advanced Print Publisher 9.1.510/W Unicode
2023-11-26T11:45:51-08:00
application/pdf
NEUROLOGY2015696120 13..20
uuid:3e355b13-af1b-4e6b-88fa-fd7e142d0237
uuid:382f3570-1dd2-11b2-0a00-8100f85a81ff
endstream
endobj
66 0 obj
<>
endobj
2 0 obj
<>
endobj
18 0 obj
<>/ExtGState<>/Font<>/ProcSet[/PDF/Text/ImageC]/Properties<>/XObject<>>>/Rotate 0/TrimBox[36 36 630 818.64]/Type/Page>>
endobj
19 0 obj
<>/ExtGState<>/Font<>/ProcSet[/PDF/Text/ImageB]/XObject<>>>/Rotate 0/TrimBox[36 36 630 818.64]/Type/Page>>
endobj
1 0 obj
<>/ExtGState<>/Font<>/ProcSet[/PDF/Text]>>/Rotate 0/TrimBox[36 36 630 818.64]/Type/Page>>
endobj
20 0 obj
<>/ExtGState<>/Font<>/ProcSet[/PDF/Text]>>/Rotate 0/TrimBox[36 36 630 818.64]/Type/Page>>
endobj
21 0 obj
<>/ExtGState<>/Font<>/ProcSet[/PDF/Text]>>/Rotate 0/TrimBox[36 36 630 818.64]/Type/Page>>
endobj
22 0 obj
<>/ExtGState<>/Font<>/ProcSet[/PDF/Text]>>/Rotate 0/TrimBox[36 36 630 818.64]/Type/Page>>
endobj
23 0 obj
<>/ExtGState<>/Font<>/ProcSet[/PDF/Text]>>/Rotate 0/TrimBox[36 36 630 818.64]/Type/Page>>
endobj
24 0 obj
<>/ExtGState<>/Font<>/ProcSet[/PDF/Text]>>/Rotate 0/TrimBox[36 36 630 818.64]/Type/Page>>
endobj
100 0 obj
<>/ProcSet[/PDF/Text/ImageB/ImageC]/XObject<>>>/Type/Page>>
endobj
109 0 obj
[116 0 R 117 0 R 118 0 R 119 0 R 120 0 R 121 0 R 122 0 R 123 0 R 124 0 R 125 0 R 126 0 R 127 0 R]
endobj
110 0 obj
<>stream
q
192 0 0 51 237 695 cm
/Im0 Do
Q
BT
/T1_0 1 Tf
12 0 0 12 236.50809 606.99988 Tm
(DOI 10.1212/WNL.0000000000002933)Tj
6.7765 1 Td
(2016;87;S13-S20 )Tj
/T1_1 1 Tf
-4.47201 0 Td
(Neurology\240)Tj
/T1_0 1 Tf
-6.80501 1.00001 Td
(Scott R. Plotkin, Stephanie D. Davis, Kent A. Robertson, et al. )Tj
/T1_2 1 Tf
11.50002 1 Td
(NF1)Tj
-17.47198 1 Td
(Sleep and pulmonary outcomes for clinical trials of airway plexiform neu\
rofibromas in)Tj
ET
BT
/T1_2 1 Tf
12 0 0 12 207.49805 580 Tm
(This information is current as of August 15, 2016)Tj
ET
108 261 450 311 re
0 0 m
S
BT
/T1_2 1 Tf
10 0 0 10 118 542.99997 Tm
(Services)Tj
0 1 TD
(Updated Information &)Tj
ET
BT
/T1_0 1 Tf
10 0 0 10 505.06973 542.99997 Tm
( )Tj
0 0 1 rg
-23.80697 0 Td
(http://n.neurology.org/content/87/7_Supplement_1/S13.full)Tj
0 g
T*
(including high resolution figures, can be found at:)Tj
ET
BT
/T1_2 1 Tf
10 0 0 10 118 520 Tm
(Supplementary Material)Tj
ET
BT
/T1_0 1 Tf
10 0 0 10 303.39005 499.99994 Tm
( )Tj
0 0 1 rg
-3.639 0 Td
(933.DC1)Tj
T*
(http://n.neurology.org/content/suppl/2016/08/15/WNL.0000000000002)Tj
0 g
0 1.00001 TD
(Supplementary material can be found at: )Tj
ET
BT
/T1_2 1 Tf
10 0 0 10 118 482 Tm
(References)Tj
ET
BT
/T1_0 1 Tf
10 0 0 10 545.05951 471.99997 Tm
( )Tj
0 0 1 rg
-27.80595 0 Td
(http://n.neurology.org/content/87/7_Supplement_1/S13.full#ref-list-1)Tj
0 g
0 1 TD
(This article cites 40 articles, 4 of which you can access for free at: )Tj
ET
BT
/T1_2 1 Tf
10 0 0 10 118 454 Tm
(Citations)Tj
ET
BT
/T1_0 1 Tf
10 0 0 10 278.11005 433.99994 Tm
( )Tj
0 0 1 rg
-1.111 0 Td
(les)Tj
T*
(http://n.neurology.org/content/87/7_Supplement_1/S13.full##otherartic)Tj
0 g
0 1.00001 TD
(This article has been cited by 2 HighWire-hosted articles: )Tj
ET
BT
/T1_2 1 Tf
10 0 0 10 118 416 Tm
(Subspecialty Collections)Tj
ET
BT
/T1_0 1 Tf
10 0 0 10 487.54974 335.99976 Tm
( )Tj
0 0 1 rg
-22.05497 0 Td
(http://n.neurology.org/cgi/collection/neurofibromatosis)Tj
0 g
/T1_2 1 Tf
0 1 TD
(Neurofibromatosis)Tj
/T1_0 1 Tf
19.88796 1.00001 Td
( )Tj
0 0 1 rg
-19.88796 0 Td
(http://n.neurology.org/cgi/collection/nerve_tumor)Tj
0 g
/T1_2 1 Tf
T*
(Nerve tumor)Tj
/T1_0 1 Tf
3.611 1 Td
( )Tj
0 0 1 rg
-3.611 0 Td
(_design_)Tj
0 1.00001 TD
(http://n.neurology.org/cgi/collection/clinical_trials_methodology_study)Tj
0 g
/T1_2 1 Tf
0 1 TD
(Clinical trials Methodology/study design)Tj
/T1_0 1 Tf
T*
(following collection\(s\): )Tj
T*
(This article, along with others on similar topics, appears in the)Tj
ET
BT
/T1_0 1 Tf
10 0 0 10 118 307.99997 Tm
(\240 )Tj
/T1_2 1 Tf
T*
(Permissions & Licensing)Tj
ET
BT
/T1_0 1 Tf
10 0 0 10 524.7699 297.99994 Tm
( )Tj
0 0 1 rg
-25.77699 0 Td
(http://www.neurology.org/about/about_the_journal#permissions)Tj
0 g
T*
(its entirety can be found online at:)Tj
0 1.00001 TD
(Information about reproducing this article in parts \(figures,tables\) o\
r in)Tj
ET
BT
/T1_0 1 Tf
10 0 0 10 118 269.99997 Tm
(\240 )Tj
/T1_2 1 Tf
0 1 TD
(Reprints)Tj
ET
BT
/T1_0 1 Tf
10 0 0 10 441.4299 269.99997 Tm
( )Tj
0 0 1 rg
-17.44299 0 Td
(http://n.neurology.org/subscribers/advertise)Tj
0 g
T*
(Information about ordering reprints can be found online:)Tj
ET
108 209 450 46 re
0 0 m
S
BT
/T1_0 1 Tf
10 0 0 10 113 216.99994 Tm
(rights reserved. Print ISSN: 0028-3878. Online ISSN: 1526-632X.)Tj
T*
(1951, it is now a weekly with 48 issues per year. Copyright \251 2016 Am\
erican Academy of Neurology. All )Tj
4.47202 1.00001 Td
(\256 is the official journal of the American Academy of Neurology. Publi\
shed continuously since)Tj
/T1_1 1 Tf
-4.47202 0 Td
(Neurology\240)Tj
ET
q
246.75 0 0 77.25 209.625 113.75 cm
-1 TL /Im1 Do
Q
endstream
endobj
114 0 obj
<>stream
y]Cz+z]zk+ y܉7 zۉ6+ k]z ʸykzCyzyz zPl + z y z y z zk k 6 z]C+ z]C6 7Oz ] ʁO 6ʩzO ]ʁ ]C yl ]ʁ C 6 ʹk k z 6 l k C ] ]]B + ۹ z 6 ʁz C k 6 z ] Bz ʻz ]y 6+ y z ] O z y y y y * z z ʾ B z + C z 6 yz ] z6z P6 z C z + By Bz Bz 7]z P zy6] ]y y CC y y B7 y z zy C zz ^ PB ! y y y BkyC+B C 7 B zz O+C C 7B zz ]] B^ O Czz ^CBCBCP B B C ] B z y 6 B y B6 z Cz y ] 6 B C zz 66 zl B C zy z C Czy BzBk C z y zy C ] + C zz CO z B6 7 C zz z y6 C+ BBz6 zy +P*z C ]CzC z z ] C* B k B ykBC6+BClyʈ6 l+k] zʉPC6Oʩy^BC6 CBPz y zBCB 6ClyʙzBC7+BCPz ] C7z C B zk6 7zۙ]+ O ^ z+ yʉC 7k y ]+ +^ۉP 6]ۂ ] z C k C z] 6lC +zB+] zy ]k+ ^ z O 7C 6kCBC]zyz yzyz]BC PCz zyzCBCk+ ʹ6 C] B zB zyz^BC+ BzyzPC 7 C y kC + z ] ]+ 6 ] k C C B zB + ] B B zC + +z ] ]* zz B z6 ]k+ C6 ! C zP kC ] + z k+ + z] kC P z C y ^ B 6 C z 7kʹ]+ 7 C z ] yP BPBzzO O z +]ʹl7 + ]l+ ] + lBCPC 6 C z ]+] + z z C y* +O z B ]z k kzC zP+ CkzkB Bk B ]C z7+C ] z] y ^ Bz z Py 6]6 k+ Pz+ ] B ] Bz+! ^ 6y z* y l B6 C ] z P ! ] ] B 7 7 C By!B] B6 z C ]]C k+]6 6 z] 6 ] ] C6 kO C ] Cy lB6 z6 C+ 7 ]6 y ] 6 z 6 O+ z ] C] B y+ z CP 6zy CC lO Cz ]* z P y 6C7 Bz7 ]]6 z P B 6+ O6 ^ y ] + k C ۷ B7 B z ^ z z C ] 7+ z ^ 7 ] + B 7 Cy ]^ z BC ]] C P z O 6 ] C y ] k O C 7C y 6 7 ! z C +kCBy ] O + z C k + O C OB y C B y B k y O z l k BC B ]Cz P C k zB B B l y z ^O ^ C +B k l C z+ + C yCB P C z ! lz B 6 B C ] By z + zBB C ! Py z z C B C] CB 6 B z k6 zB BB y B y B ] O z+ C y B6 B z y zz7 y BCC ] z ^ O P C+ 6+ B C Cz* kyzyzyzylCBCBC z C CCz ] Pz 7 z Ck C B z zB C B 7 + z y 6 k Cl ] C B 6C zC zB B B C k z + z +z B 7+ C 6 B z C z C CB C O 7 6z 6 ] C yC C z ]B y l zB C C C k y ] y k C B l+ C ] ] Cz 6 O y B BBP P y + 6B ] O C C P Bz +kz yz yzyz yzyzyzyz z B CB z O ^ z O C z C C6 Bz + yC CB y 6z z z C C ] 7 B* B yk z z B B B z y B k z P ] ] C C z 6 yB C B z C +z O z z + C B z y B C Cz lC B z C B O +] B Cy zC B C yB Cz yz z + + B 7C z zB C B y+ z z zy l C]6Cz zy yCCB z y By y 6 O k C P 6 OC+ B ] PB y] y zC B Cy y C z] C+ B6 ] ByC zz BC B y z B z BC * ] + C6 ] B y C] y BB C z y C z B ^ ]+O] 6 z C C z 6 B yC CC y y Cy B y + z +y B y + y C B Cz y C z C z ] z *z Cz yB B C y k Cz Bz ! O O k 6 y Cz z B B C z C O y C z C Cyz z B y z z C C B z C y z B z P k + z y ] C y P y B C B z + zz ] z 6 +] y z C B y C zC BCz z yyO B ]] y7 zB y C C C z+ z z k C ]*!+ B ] z zz + zC ] y B CC z B z CCy6 *ۙ6 z z z z C B B yk z 6y P C]z]C+C z z y y BB B z O z ]z ! ] P + P z C z C C C z +] zB 6C k z C y yC CB y ! C z y k k k+y + + B z ] z 6 C z C CBy O 6y + z C +ll+ ]C y ^ y k z B B C z P k z C CB* 6Cz + ۢC y6 z 6 ] B C C y z ] ! ] P ܸ 6 ] ] P6z B C B B z O ] 6z 6 + ۡ C z P 6 B B B y O * z+ + 6ʩ z]B z 6 6 C y zy kC 6P*+ ۡ z ] C y z yk zy + * ] z y zy B y !+ z y ʠ ʸ ]y C+ C 7 C z y y + + + ] ] B ] y ^ z+ C+C* C + z z ]ʣ y y6 z ]6] z C z y + B O6 + C C ]6 y y 77^y * B P C k y l B l 6 7 z+ z+ k6 l B 76 ] k * O B C z + 6 6 k+ B 6 z k6 + y k +B B 6 + O 6 z 6 O * l O z6 ]] ] y ] ] P 6+ + ۳] y Ckl+ kz C l] ]67 C 6 + ] 7 B O ^ yO z]7y ] C 666 6ʣ k O+6 B 6kzC+ O l P] ] C P ] ʉB ]۷ C+ k k 6 ]+ + +]6 O^k Oz zyzy]CB Cz y۹zBC 6CPz C6 67 BB ʨy]B+CBz y + +B CzlC+ 6Pz k ]] + By B + B y ] C ]k CyP ] + *]k+ P ^ ] z ] kB6 *!!zC y C ] Py + O Cy C P B z+ z C Clz + C B] +6 O z] z7+z+ zl zC 6k 7B ] 6 l] +6 z ܧy!CBPzyz yz CBCB+6 P 6P P C Cz76C^zyz z yz yzyOCBC6 k+ 6 CBC]yzyz z yzykCBC*+P ]6 k ] +O B܈6 O C +kyC +Oۥ]+ CyP Bہ k ʨyPB* 6BkyPC+7Bk C+lʕʘyBC+CB]y۹z]BC +By Py O]z 6 ] ^ہ6 BC + 6 ] CPyz yzyz yz kC 6 6lۨl+ O z6C] ++6 z] 6 C 6 7 lz6 C ] 6y B z 7 l C] ہ B ] ]]C ] ہ C ] B C ] 6z C! CB l 7 B z +C C z P z* B P z B B P B B ] z ! + ]Bk^ ہ Oz ] ]+ y+ B ]C O Ck y k ] 7 7] + ] 7 ] ] z P ]B z] 6 6 zB6 ] y6 ^ ہ] O] y C 6kʨzCB C 7B 6CBCBCB ʁ ] ] + ʁ ] +ʁC ]B z+ +]CB]C +kʁl76zʁۘ]6 +Pzʹy ]CBCkzy
endstream
endobj
115 0 obj
<>/Filter/FlateDecode/Height 309/Length 29240/Name/X/Subtype/Image/Type/XObject/Width 987>>stream
H?Hi)B@HsPp#R$cHۜZZ%VVSeK<PX Ā"!!r70d>:S=3y۷}7b @Ҿ B<M3?2{ %ȣٜZ* JkӥZ nw;