2016年7月5日
;87 (1)
文章
胆囊息肉的风险和癌异染性脑白质营养不良
黛安·f·范·Rappard,玛丽安娜Bugiani,傻瓜j . Boelens,智囊机构fw van der Steeg,Freek Daams,蒂姆G.J. de Meij,马丁尼M.A.C.范·多尔恩,彼得·m·范特,德克·j·Gouma,乔纳森I.M.L.韦贝克,卡拉E.M. Hollak,维姆·范·Hecke,Gajja美国所罗门,Marjo美国范德Knaap,妮可:狼
第一次出版2016年6月3日,
DOI: https://doi.org/10.1212/WNL.0000000000002811
黛安·f·范·Rappard
从儿童神经病学,童年白质异常和神经科学中心校园阿姆斯特丹(首页D.F.v.R M.S.v.d.K。,N.I.W.), Department of Pathology, Center for Childhood White Matter Disorders (M.B.), and Departments of Surgery (F.D.), Pediatric Gastroenterology (T.G.J.d.M.), and Radiology (M.M.A.C.v.D., J.I.M.L.V.), VU University Medical Center Amsterdam; Department of Pediatrics, Blood and Marrow Transplantation Program (J.J.B.), and Departments of Metabolic Disorders (P.M.v.H.) and Pathology (W.v.H.), University Medical Center Utrecht; Pediatric Surgical Center of Amsterdam (A.F.W.v.d.S.), Emma Children's Hospital Academic Medical Center and VU University Medical Center Amsterdam; Department of Surgery (D.J.G.), and Department of Internal Medicine, Division of Endocrinology and Metabolism (C.E.M.H.), Academic Medical Center Amsterdam; and Department of Clinical Chemistry (G.S.S.), VU Medical Center and Neuroscience Campus Amsterdam, the Netherlands.
玛丽安娜Bugiani
从儿童神经病学,童年白质异常和神经科学中心校园阿姆斯特丹(首页D.F.v.R M.S.v.d.K。,N.I.W.), Department of Pathology, Center for Childhood White Matter Disorders (M.B.), and Departments of Surgery (F.D.), Pediatric Gastroenterology (T.G.J.d.M.), and Radiology (M.M.A.C.v.D., J.I.M.L.V.), VU University Medical Center Amsterdam; Department of Pediatrics, Blood and Marrow Transplantation Program (J.J.B.), and Departments of Metabolic Disorders (P.M.v.H.) and Pathology (W.v.H.), University Medical Center Utrecht; Pediatric Surgical Center of Amsterdam (A.F.W.v.d.S.), Emma Children's Hospital Academic Medical Center and VU University Medical Center Amsterdam; Department of Surgery (D.J.G.), and Department of Internal Medicine, Division of Endocrinology and Metabolism (C.E.M.H.), Academic Medical Center Amsterdam; and Department of Clinical Chemistry (G.S.S.), VU Medical Center and Neuroscience Campus Amsterdam, the Netherlands.
傻瓜j . Boelens
从儿童神经病学,童年白质异常和神经科学中心校园阿姆斯特丹(首页D.F.v.R M.S.v.d.K。,N.I.W.), Department of Pathology, Center for Childhood White Matter Disorders (M.B.), and Departments of Surgery (F.D.), Pediatric Gastroenterology (T.G.J.d.M.), and Radiology (M.M.A.C.v.D., J.I.M.L.V.), VU University Medical Center Amsterdam; Department of Pediatrics, Blood and Marrow Transplantation Program (J.J.B.), and Departments of Metabolic Disorders (P.M.v.H.) and Pathology (W.v.H.), University Medical Center Utrecht; Pediatric Surgical Center of Amsterdam (A.F.W.v.d.S.), Emma Children's Hospital Academic Medical Center and VU University Medical Center Amsterdam; Department of Surgery (D.J.G.), and Department of Internal Medicine, Division of Endocrinology and Metabolism (C.E.M.H.), Academic Medical Center Amsterdam; and Department of Clinical Chemistry (G.S.S.), VU Medical Center and Neuroscience Campus Amsterdam, the Netherlands.
智囊机构fw van der Steeg
从儿童神经病学,童年白质异常和神经科学中心校园阿姆斯特丹(首页D.F.v.R M.S.v.d.K。,N.I.W.), Department of Pathology, Center for Childhood White Matter Disorders (M.B.), and Departments of Surgery (F.D.), Pediatric Gastroenterology (T.G.J.d.M.), and Radiology (M.M.A.C.v.D., J.I.M.L.V.), VU University Medical Center Amsterdam; Department of Pediatrics, Blood and Marrow Transplantation Program (J.J.B.), and Departments of Metabolic Disorders (P.M.v.H.) and Pathology (W.v.H.), University Medical Center Utrecht; Pediatric Surgical Center of Amsterdam (A.F.W.v.d.S.), Emma Children's Hospital Academic Medical Center and VU University Medical Center Amsterdam; Department of Surgery (D.J.G.), and Department of Internal Medicine, Division of Endocrinology and Metabolism (C.E.M.H.), Academic Medical Center Amsterdam; and Department of Clinical Chemistry (G.S.S.), VU Medical Center and Neuroscience Campus Amsterdam, the Netherlands.
Freek Daams
从儿童神经病学,童年白质异常和神经科学中心校园阿姆斯特丹(首页D.F.v.R M.S.v.d.K。,N.I.W.), Department of Pathology, Center for Childhood White Matter Disorders (M.B.), and Departments of Surgery (F.D.), Pediatric Gastroenterology (T.G.J.d.M.), and Radiology (M.M.A.C.v.D., J.I.M.L.V.), VU University Medical Center Amsterdam; Department of Pediatrics, Blood and Marrow Transplantation Program (J.J.B.), and Departments of Metabolic Disorders (P.M.v.H.) and Pathology (W.v.H.), University Medical Center Utrecht; Pediatric Surgical Center of Amsterdam (A.F.W.v.d.S.), Emma Children's Hospital Academic Medical Center and VU University Medical Center Amsterdam; Department of Surgery (D.J.G.), and Department of Internal Medicine, Division of Endocrinology and Metabolism (C.E.M.H.), Academic Medical Center Amsterdam; and Department of Clinical Chemistry (G.S.S.), VU Medical Center and Neuroscience Campus Amsterdam, the Netherlands.
蒂姆G.J. de Meij
从儿童神经病学,童年白质异常和神经科学中心校园阿姆斯特丹(首页D.F.v.R M.S.v.d.K。,N.I.W.), Department of Pathology, Center for Childhood White Matter Disorders (M.B.), and Departments of Surgery (F.D.), Pediatric Gastroenterology (T.G.J.d.M.), and Radiology (M.M.A.C.v.D., J.I.M.L.V.), VU University Medical Center Amsterdam; Department of Pediatrics, Blood and Marrow Transplantation Program (J.J.B.), and Departments of Metabolic Disorders (P.M.v.H.) and Pathology (W.v.H.), University Medical Center Utrecht; Pediatric Surgical Center of Amsterdam (A.F.W.v.d.S.), Emma Children's Hospital Academic Medical Center and VU University Medical Center Amsterdam; Department of Surgery (D.J.G.), and Department of Internal Medicine, Division of Endocrinology and Metabolism (C.E.M.H.), Academic Medical Center Amsterdam; and Department of Clinical Chemistry (G.S.S.), VU Medical Center and Neuroscience Campus Amsterdam, the Netherlands.
马丁尼M.A.C.范·多尔恩
从儿童神经病学,童年白质异常和神经科学中心校园阿姆斯特丹(首页D.F.v.R M.S.v.d.K。,N.I.W.), Department of Pathology, Center for Childhood White Matter Disorders (M.B.), and Departments of Surgery (F.D.), Pediatric Gastroenterology (T.G.J.d.M.), and Radiology (M.M.A.C.v.D., J.I.M.L.V.), VU University Medical Center Amsterdam; Department of Pediatrics, Blood and Marrow Transplantation Program (J.J.B.), and Departments of Metabolic Disorders (P.M.v.H.) and Pathology (W.v.H.), University Medical Center Utrecht; Pediatric Surgical Center of Amsterdam (A.F.W.v.d.S.), Emma Children's Hospital Academic Medical Center and VU University Medical Center Amsterdam; Department of Surgery (D.J.G.), and Department of Internal Medicine, Division of Endocrinology and Metabolism (C.E.M.H.), Academic Medical Center Amsterdam; and Department of Clinical Chemistry (G.S.S.), VU Medical Center and Neuroscience Campus Amsterdam, the Netherlands.
彼得·m·范特
从儿童神经病学,童年白质异常和神经科学中心校园阿姆斯特丹(首页D.F.v.R M.S.v.d.K。,N.I.W.), Department of Pathology, Center for Childhood White Matter Disorders (M.B.), and Departments of Surgery (F.D.), Pediatric Gastroenterology (T.G.J.d.M.), and Radiology (M.M.A.C.v.D., J.I.M.L.V.), VU University Medical Center Amsterdam; Department of Pediatrics, Blood and Marrow Transplantation Program (J.J.B.), and Departments of Metabolic Disorders (P.M.v.H.) and Pathology (W.v.H.), University Medical Center Utrecht; Pediatric Surgical Center of Amsterdam (A.F.W.v.d.S.), Emma Children's Hospital Academic Medical Center and VU University Medical Center Amsterdam; Department of Surgery (D.J.G.), and Department of Internal Medicine, Division of Endocrinology and Metabolism (C.E.M.H.), Academic Medical Center Amsterdam; and Department of Clinical Chemistry (G.S.S.), VU Medical Center and Neuroscience Campus Amsterdam, the Netherlands.
德克·j·Gouma
从儿童神经病学,童年白质异常和神经科学中心校园阿姆斯特丹(首页D.F.v.R M.S.v.d.K。,N.I.W.), Department of Pathology, Center for Childhood White Matter Disorders (M.B.), and Departments of Surgery (F.D.), Pediatric Gastroenterology (T.G.J.d.M.), and Radiology (M.M.A.C.v.D., J.I.M.L.V.), VU University Medical Center Amsterdam; Department of Pediatrics, Blood and Marrow Transplantation Program (J.J.B.), and Departments of Metabolic Disorders (P.M.v.H.) and Pathology (W.v.H.), University Medical Center Utrecht; Pediatric Surgical Center of Amsterdam (A.F.W.v.d.S.), Emma Children's Hospital Academic Medical Center and VU University Medical Center Amsterdam; Department of Surgery (D.J.G.), and Department of Internal Medicine, Division of Endocrinology and Metabolism (C.E.M.H.), Academic Medical Center Amsterdam; and Department of Clinical Chemistry (G.S.S.), VU Medical Center and Neuroscience Campus Amsterdam, the Netherlands.
乔纳森I.M.L.韦贝克
从儿童神经病学,童年白质异常和神经科学中心校园阿姆斯特丹(首页D.F.v.R M.S.v.d.K。,N.I.W.), Department of Pathology, Center for Childhood White Matter Disorders (M.B.), and Departments of Surgery (F.D.), Pediatric Gastroenterology (T.G.J.d.M.), and Radiology (M.M.A.C.v.D., J.I.M.L.V.), VU University Medical Center Amsterdam; Department of Pediatrics, Blood and Marrow Transplantation Program (J.J.B.), and Departments of Metabolic Disorders (P.M.v.H.) and Pathology (W.v.H.), University Medical Center Utrecht; Pediatric Surgical Center of Amsterdam (A.F.W.v.d.S.), Emma Children's Hospital Academic Medical Center and VU University Medical Center Amsterdam; Department of Surgery (D.J.G.), and Department of Internal Medicine, Division of Endocrinology and Metabolism (C.E.M.H.), Academic Medical Center Amsterdam; and Department of Clinical Chemistry (G.S.S.), VU Medical Center and Neuroscience Campus Amsterdam, the Netherlands.
卡拉E.M. Hollak
从儿童神经病学,童年白质异常和神经科学中心校园阿姆斯特丹(首页D.F.v.R M.S.v.d.K。,N.I.W.), Department of Pathology, Center for Childhood White Matter Disorders (M.B.), and Departments of Surgery (F.D.), Pediatric Gastroenterology (T.G.J.d.M.), and Radiology (M.M.A.C.v.D., J.I.M.L.V.), VU University Medical Center Amsterdam; Department of Pediatrics, Blood and Marrow Transplantation Program (J.J.B.), and Departments of Metabolic Disorders (P.M.v.H.) and Pathology (W.v.H.), University Medical Center Utrecht; Pediatric Surgical Center of Amsterdam (A.F.W.v.d.S.), Emma Children's Hospital Academic Medical Center and VU University Medical Center Amsterdam; Department of Surgery (D.J.G.), and Department of Internal Medicine, Division of Endocrinology and Metabolism (C.E.M.H.), Academic Medical Center Amsterdam; and Department of Clinical Chemistry (G.S.S.), VU Medical Center and Neuroscience Campus Amsterdam, the Netherlands.
维姆·范·Hecke
从儿童神经病学,童年白质异常和神经科学中心校园阿姆斯特丹(首页D.F.v.R M.S.v.d.K。,N.I.W.), Department of Pathology, Center for Childhood White Matter Disorders (M.B.), and Departments of Surgery (F.D.), Pediatric Gastroenterology (T.G.J.d.M.), and Radiology (M.M.A.C.v.D., J.I.M.L.V.), VU University Medical Center Amsterdam; Department of Pediatrics, Blood and Marrow Transplantation Program (J.J.B.), and Departments of Metabolic Disorders (P.M.v.H.) and Pathology (W.v.H.), University Medical Center Utrecht; Pediatric Surgical Center of Amsterdam (A.F.W.v.d.S.), Emma Children's Hospital Academic Medical Center and VU University Medical Center Amsterdam; Department of Surgery (D.J.G.), and Department of Internal Medicine, Division of Endocrinology and Metabolism (C.E.M.H.), Academic Medical Center Amsterdam; and Department of Clinical Chemistry (G.S.S.), VU Medical Center and Neuroscience Campus Amsterdam, the Netherlands.
Gajja美国所罗门
从儿童神经病学,童年白质异常和神经科学中心校园阿姆斯特丹(首页D.F.v.R M.S.v.d.K。,N.I.W.), Department of Pathology, Center for Childhood White Matter Disorders (M.B.), and Departments of Surgery (F.D.), Pediatric Gastroenterology (T.G.J.d.M.), and Radiology (M.M.A.C.v.D., J.I.M.L.V.), VU University Medical Center Amsterdam; Department of Pediatrics, Blood and Marrow Transplantation Program (J.J.B.), and Departments of Metabolic Disorders (P.M.v.H.) and Pathology (W.v.H.), University Medical Center Utrecht; Pediatric Surgical Center of Amsterdam (A.F.W.v.d.S.), Emma Children's Hospital Academic Medical Center and VU University Medical Center Amsterdam; Department of Surgery (D.J.G.), and Department of Internal Medicine, Division of Endocrinology and Metabolism (C.E.M.H.), Academic Medical Center Amsterdam; and Department of Clinical Chemistry (G.S.S.), VU Medical Center and Neuroscience Campus Amsterdam, the Netherlands.
Marjo美国范德Knaap
从儿童神经病学,童年白质异常和神经科学中心校园阿姆斯特丹(首页D.F.v.R M.S.v.d.K。,N.I.W.), Department of Pathology, Center for Childhood White Matter Disorders (M.B.), and Departments of Surgery (F.D.), Pediatric Gastroenterology (T.G.J.d.M.), and Radiology (M.M.A.C.v.D., J.I.M.L.V.), VU University Medical Center Amsterdam; Department of Pediatrics, Blood and Marrow Transplantation Program (J.J.B.), and Departments of Metabolic Disorders (P.M.v.H.) and Pathology (W.v.H.), University Medical Center Utrecht; Pediatric Surgical Center of Amsterdam (A.F.W.v.d.S.), Emma Children's Hospital Academic Medical Center and VU University Medical Center Amsterdam; Department of Surgery (D.J.G.), and Department of Internal Medicine, Division of Endocrinology and Metabolism (C.E.M.H.), Academic Medical Center Amsterdam; and Department of Clinical Chemistry (G.S.S.), VU Medical Center and Neuroscience Campus Amsterdam, the Netherlands.
妮可:狼
从儿童神经病学,童年白质异常和神经科学中心校园阿姆斯特丹(首页D.F.v.R M.S.v.d.K。,N.I.W.), Department of Pathology, Center for Childhood White Matter Disorders (M.B.), and Departments of Surgery (F.D.), Pediatric Gastroenterology (T.G.J.d.M.), and Radiology (M.M.A.C.v.D., J.I.M.L.V.), VU University Medical Center Amsterdam; Department of Pediatrics, Blood and Marrow Transplantation Program (J.J.B.), and Departments of Metabolic Disorders (P.M.v.H.) and Pathology (W.v.H.), University Medical Center Utrecht; Pediatric Surgical Center of Amsterdam (A.F.W.v.d.S.), Emma Children's Hospital Academic Medical Center and VU University Medical Center Amsterdam; Department of Surgery (D.J.G.), and Department of Internal Medicine, Division of Endocrinology and Metabolism (C.E.M.H.), Academic Medical Center Amsterdam; and Department of Clinical Chemistry (G.S.S.), VU Medical Center and Neuroscience Campus Amsterdam, the Netherlands.
胆囊息肉的风险和癌异染性脑白质营养不良
黛安·F。范Rappard,玛丽安娜Bugiani,傻瓜J。Boelens,智囊机构fwvan der Steeg,FreekDaams,蒂姆G.J.de Meij,马丁尼M.A.C.范·多尔恩,彼得·M。范特,德克·J。Gouma,乔纳森I.M.L.韦贝克,卡拉。Hollak,埃姆范Hecke,Gajja年代。所罗门,Marjo年代。van der Knaap,妮可我。狼
首页
2016年7月,
87年
(1)
103 188金宝慱官网下载- 111;
DOI:10.1212 / WNL.0000000000002811
做出评论
看到评论
这篇文章需要订阅查看全文。如果你有一个订阅你可以用下面的登录表单查看文章。这篇文章也可以购买。
文摘
目的:评估胆囊息肉病的频率和癌异染性脑白质营养不良(MLD)。
方法:我们评估34 MLD患者(平均年龄16.7岁,年龄范围2-39年)胆囊异常超声筛查。在胆囊切除术中,在综述了病理结果。
结果:只有8的34个病人(23%)有正常胆囊超声波。胆囊息肉是可见的8例(23%)。胆囊切除术11个患者(32%)。在这些病理显示各种异常,包括增生性息肉、肠上皮化生,突出Rokitansky-Aschoff鼻窦,硫苷脂存储。
结论:我们的结果表明,胆囊参与MLD的规则,而不是例外。增生性息肉患病率高,一个已知的癌前病变,一个死于胆囊癌在年轻的时候表明MLD易诱发肿瘤胆囊异常。作为小说治疗这个病人群体出现导致平均寿命增加,我们建议胆囊异常超声筛查,以防止过早死亡。
术语表
- HSCT=
- 造血干细胞移植;
- MLD=
- 异染性脑白质营养不良
脚注
↵*这些作者的贡献同样作为联合的高级作者。
去首页Neurology.org为充分披露。资金信息和披露认为作者相关的,如果有的话,年底提供这篇文章。
- 收到了2015年12月14日。
- 接受的最终形式2016年3月21日。
- ©2016美国神经病学学会的首页
寻求帮助,请联系:
河畔成员(800)879 - 1960或(612)928 - 6000(国际)
Non-AAN会员用户(800)638 - 3030或(301)223 - 2300选项3,选择1(国际)
报名
信息订阅神经病学和神经学:临床实践中可以找到首页在这里
购买
个人访问的文章可以通过这篇文章页面上加入购物车选项。获得1天(从您目前正在使用的计算机)是39.00美元。按次计费的内容仅供使用收款人和内容可能不会进一步分布式打印或电子手段。收款人可以查看、下载或打印文章为他/她的个人、学术研究和教学使用。分发副本(电子或其他方式)的文章是不允许的。
信:快速的网络通信
你可能也会感兴趣
广告
相关文章
-
没有找到相关文章。
主题讨论
提醒我
推荐的文章
- 简短的沟通
青少年晚期异染性脑白质营养不良治疗骨髓移植四年随访研究
c·纳瓦罗j·m·费尔南德斯·c·多明格斯et al。
首页神经学,1996年1月1日 - 文章
协会和第一症状与发病年龄在异染性脑白质营养不良患者疾病进展克丽丝汀Kehrer, Saskia Elgun, Christa·拉伯等。
首页神经学,2020年10月12日 - 审查
脑白质营养不良五个新事物
Marjo s . van der Knaap妮可狼,昕薇·m·海涅等。
首页神经学:临床实践,2016年8月23日 - 文章
脑灰质和白质的变化和异染性脑白质营养不良的临床过程撒母耳Groeschel Christine我大理,菲利普·高et al。
首页神经学,2012年9月19日