Status epilepticus
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Status epilepticus (SE) is a common pediatric neurologic emergency with an incidence of 10–38 per 100,000 children per year, associated with substantial morbidity and mortality.1 An operational definition of SE, sometimes called impending SE, occurs when a seizure or a series of seizures without intervening recovery of consciousness lasts 5–10 minutes. By the traditional definition, SE is not established until the duration reaches 30 minutes. Refractory SE occurs when an adequately dosed initial benzodiazepine and one other antiseizure medication have failed to stop the seizure.2 The overall short-term mortality of convulsive SE in children is notable at 3%–5%3 and is at least twice as high for refractory SE.4 Overall morbidity for convulsive SE in children is 10%–30% and over 50% for refractory SE.3 These data indicate that longer seizures result in worse outcomes.
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- © 2015 American Academy of Neurology
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