Venous angioplasty for “CCSVI” in multiple sclerosis
Ending a therapeutic misadventure
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In 1889, Charcot described the results of “suspension therapy” for tabes dorsalis and other diseases.1 The procedure entailed suspending patients from a harness attached to their chin and occiput for several minutes. The goal was to stretch the spinal cord, presumably to improve circulation. Charcot described several patients with tabes dorsalis whose symptoms improved following the treatment. However, the therapy was often painful, one patient with multiple sclerosis (MS) developed paraplegia after 2 treatments, and there were other serious side effects, including death by strangulation. Despite his initial enthusiasm for the treatment, Charcot eventually abandoned suspension therapy, displaying the wisdom to recognize a treatment that did not result in sustained benefit and carried serious risks.
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