评估残疾的多发性硬化症使用kinect摄像头系统:一个概念验证研究(P3.139)

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摘要目的:证明微软的Kinect深度传感器技术和新的图像分析算法可以用来区分健康志愿者(高压)和多发性硬化(MS)患者和分类患者水平的基础上选定的运动障碍。背景:预防神经恶化女士长期治疗的主要目标在临床评估损伤和残疾的病人护理和治疗的结果是最重要的试验。临床评估的有效性和再现性不足,尤其是在不同的评级机构。因此,我们开发了自动图像分析算法建立在Kinect深度传感器,在一个自动启用运动分析和可再生的时装使用先进的机器学习和计算机视觉技术。设计/方法:Kinect是用来捕获定义神经运动,代表上、下肢功能,和86年高压和72 MS患者躯干的稳定性。所有的患者同时接受标准化EDSS-assessment。Kinect允许录制视频以每秒30帧的深度。视频是匿名和预处理和我们的机器学习技术应用于自动测量,提取相关的高压和MS患者之间的分化。结果:我们能够捕获定义高压和MS患者的神经运动。数据分析显示集群子组的受试者显示类似的运动模式(例如抖动、运动的速度)。女士高压和未受感染的病人可以区别医学患者基于这些模式的影响。结论:可以使用Kinect结合定制图像分析算法来区分高压女士和女士未受感染病人的运动功能障碍患者,可能使分类的水平运动障碍。这一技术有可能有助于更客观的量化运动异常女士尽管结果是有前途的,需要进一步评估和额外的动作。

披露:Souza博士已经收到了诺华的研究支持。卡姆博士已经收到个人活动与补偿Idec,诺华,拜耳制药公司,默克公司Serono, Genzyme Corp .)和辉瑞公司Burggraaff博士没有披露。Tewarie博士没有披露。格洛克博士获得了与微软作为一个员工个人补偿活动。多恩博士已经收到个人活动与诺华作为雇员补偿。沃格尔博士已经收到个人活动与诺华作为雇员补偿。莫里森博士获得了与微软作为一个员工个人补偿活动。Sellen博士获得了与微软作为一个员工个人补偿活动。博士·已收到个人活动与诺华作为雇员补偿。大下巴已经收到个人活动与诺华作为雇员补偿。 Dr. Chin holds stock and/or stock options in Novartis, which sponsored research in which Dr. Chin was involved as an investigator. Dr. Uitdehaag has received personal compensation for activities with Novartis and Merck Serono as a consultant. Dr. Uitdehaag has received personal compensation in an editorial capacity for Ariez Medical Publishing. Dr. Uitdehaag has received research support from Biogen Idec, Bayer Schering Pharma, GlaxoSmithKline, Inc., Novartis, Merck Serono and Teva Neuroscience. Dr. Criminisi has received personal compensation for activities with Microsoft as an employee. Dr. Dahlke has received personal compensation for activities with Novartis as an employee. Dr. Polman has received personal compensation for activities with Biogen Idec, Schering AG, Teva Neuroscience, EMD Serono, Novartis, GlaxoSmithKline, Inc., UCB Pharma, AstraZeneca Pharmaceuticals, Roche Diagnostics Inc., Actelion, and Antisense Therapeutics as a consultant. Dr. Polman has received research support from Biogen Idec, Schering AG, GlaxoSmithKline, Inc., Novartis, EMD Serono and Teva Neuroscience. Dr. Kappos has received personal compensation for activities with the University Hospital Basel. Dr. Kappos has received research support from the Swiss MS Society, Swiss National Research Foundation, the European Union, Gianni Rubatto Foundation, Novartis, and Roche Diagnostics Corp.