治疗和预防amyloidoses:可以教训适用于零星的包涵体肌炎吗?

编辑器:

巴克斯鲍姆的优秀文章amyloidoses指的是家族性地中海热淀粉样变(FMF)。¹AA与FMF代表一个单独的实体相关的淀粉样变的疾病。尽管它是与某一分子(即背景。,pyrin gene mutations) and it is usually complicating a long manifested FMF, it may also develop in an otherwise asymptomatic state. It can be the presenting symptom of FMF called phenotype II. Accordingly, FMF amyloidosis may be a direct disease-associated condition rather than a complication of the disease inflammatory activity.

最近的进步我们理解的角色pyrin(正常和突变)在细胞凋亡和炎症支持这一假设。秋水仙碱,这种药物控制的频率和严重性FMF危机,也可能…