This article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article can also be purchased.
Hemiplegic migraine is a very rare subtype of migraine. Familial hemiplegic migraine is an autosomal dominant trait, and mutations in three different genes encoding structural proteins of voltage-gated P/Q calcium channel and the membrane sodium–potassium ATPase pump1 have been implicated in its pathogenesis. Sporadic hemiplegic migraine may reflect spontaneous mutations or incomplete penetrance.
We report a case of a severe and prolonged hemiplegic migraine attack precipitated by sedation for an endoscopic procedure in a patient with sporadic hemiplegic migraine. We reviewed the medical literature and discuss two other similar case reports.
Case reports.
A 46-year-old right-handed woman was referred for an esophagogastroscopy and pH monitoring for dysphagia and heartburn. Midazolam (6 mg) and fentanyl (50 μg) were used sequentially IV for sedation and analgesia. Following the procedure, the patient failed to regain consciousness, even after naloxone administration. She was transferred to …
AAN Members
We have changed the login procedure to improve access between AAN.com and the Neurology journals. If you are experiencing issues, please log out of AAN.com and clear history and cookies. (For instructions by browser, please click the instruction pages below). After clearing, choose preferred Journal and select login for AAN Members. You will be redirected to a login page where you can log in with your AAN ID number and password. When you are returned to the Journal, your name should appear at the top right of the page.
AAN Non-Member Subscribers
Purchase access
Letters: Rapid online correspondence
REQUIREMENTS
You must ensure that your Disclosures have been updated within the previous six months. Please go to our Submission Site to add or update your Disclosure information.
Your co-authors must send a completed Publishing Agreement Form to Neurology Staff (not necessary for the lead/corresponding author as the form below will suffice) before you upload your comment.
If you are responding to a comment that was written about an article you originally authored:
You (and co-authors) do not need to fill out forms or check disclosures as author forms are still valid
and apply to letter.
Submission specifications:
- Submissions must be < 200 words with < 5 references. Reference 1 must be the article on which you are commenting.
- Submissions should not have more than 5 authors. (Exception: original author replies can include all original authors of the article)
- Submit only on articles published within 6 months of issue date.
- Do not be redundant. Read any comments already posted on the article prior to submission.
- Submitted comments are subject to editing and editor review prior to posting.
You May Also be Interested in
Alert Me
Recommended articles
Clinical spectrum of hemiplegic migraine and chances of finding a pathogenic mutation
A randomized controlled trial of intranasal ketamine in migraine with prolonged aura
Aura in some patients with familial hemiplegic migraine can be stopped by intranasal ketamine
Systematic analysis of three FHM genes in 39 sporadic patients with hemiplegic migraine