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Abstract
The contribution of extracranial tissue damage to serum S100β increases was examined in 18 marathon runners without clinical or laboratory signs of brain damage. Postrace serum S100β and creatine kinase (CK) concentrations increased (p < 0.001), and areas under the curve were highly correlated (p = 0.001). To conclude, serum S100β increases after running originate from extracranial sources. CK determination may improve specificity of S100β as a marker of brain tissue damage in acute trauma.
- Received October 17, 2003.
- Accepted in final form December 23, 2003.
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