Analgesic use: A predictor of chronic pain in medication overuse headache: The Head-HUNT Study
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To the Editor:
We were delighted by the inclusion of both the article by Zwart et al.1 and the accompanying editorial by Lipton and Bigal2 on the clinical issues of both chronic daily headache and rebound. However, we believe that any article exploring the role of analgesic overuse and chronic daily headache should acknowledge the pioneering work that appeared in 1982 that first laid out the paradoxical effects of frequent analgesic use and the clinical benefits of discontinuation of these medications. Two studies appeared at around the same time that year by two giants in headache care who simultaneously reported similar results. Alphabetically ordered, the first study was by the Swiss neurologist …
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