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Abstract
Article abstract Sera from patients with MS treated with recombinant interferon (rIFN) α-2a, rIFNβ-1a, or rIFNβ-1b were analyzed for cross-reacting neutralizing antibodies (NAB). Because cross-reactivity was not found, switching treatment from rIFNβ-1a or rIFNβ-1b to rIFNα-2a might provide a secondary treatment response in patients with NAB to rIFNβ-1a or rIFNβ-1b. A positive treatment response also might be achieved by switching NAB rIFNα-2a–positive patients to rIFNβ-1a or rIFNβ-1b.–1571
- Received March 16, 2000.
- Accepted July 19, 2000.
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