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Dropped head syndrome
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Reply from the Authors: We appreciate the comments by Drs. Jaster and Waclawik et al. regarding our study of INEM. [1] Although none of our patients had an inflammatory myopathy on histology, we did postulate that a focal inflammatory process that later resolves may be responsible for the neck extensor weakness. Jaster et al. describe an elderly man with weakness restricted to neck extensors who did have necrosis and scattered inflammatory cells on muscle biopsy. Their case lends support to an inflammatory hypothesis, and we look forward to reading their paper when it is published.
Waclawik et al. raise several important points. Many, if not most, patients with myopathic DHS have mild weakness of shoulder girdle and proximal arm muscles …
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ARTICLES
Isolated neck extensor myopathyA common cause of dropped head syndromeJ. S. Katz, G. I. Wolfe, D. K. Burns et al.Neurology, April 01, 1996 -
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Isolated dropped head due to adult-onset nemaline myopathy treated by posterior fusionB. Katirji, R. Hachwi, A. Al-Shekhlee et al.Neurology, November 07, 2005 -
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Long-term Follow-up and Muscle Imaging Findings in Brachio-Cervical Inflammatory MyopathyMatteo Lucchini, Sara Bortolani, Mauro Monforte et al.Neurology: Neuroimmunology & Neuroinflammation, May 19, 2021 -
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Clinical Reasoning: A 38-year-old woman with childhood-onset weaknessPartha S. Ghosh, Margherita Milone et al.Neurology, August 11, 2014