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不良反应通常发生在艾滋病患者治疗功效(TMP / SMX)卡氏肺孢子虫肺炎(PCP)。磺胺类药物不耐受是10倍比一般人群艾滋病病毒感染者。[1]皮肤(皮疹,荨麻疹),胃肠道(恶心、呕吐、厌食)、血液(白血球减少症)是最常见的副作用。然而,许多不良神经反应可能发生,包括头痛、无菌性脑膜炎、共济失调、周围神经炎、癫痫、幻觉、震颤。[2]都是潜在可逆的TMP / SMX或停止,在某些情况下,只有减少剂量。我报告艾滋病患者接受TMP / SMX的卡式肺囊虫肺炎了姿势和动能地震没有其他气孔的TMP / SMX-induced反应,它解决了停药。
病例报告。
一名46岁男子与一个6年的艾滋病是评估的历史“震动”。He was on day 13 of TMP/SMX treatment (320 mg of trimethoprim and 1,600 mg of sulfamethoxazole three times daily) for PCP and had experienced increasing tremulousness over the preceding 10 days. His other medications included paroxetine, didanosine (ddI), prednisone, leucovorin, clotrimazole, and diazepam, none of which had been started recently. The tremor involved his head and all extremities, and he had noticed a precipitous …
