这篇文章需要订阅查看全文。如果你有一个订阅你可以用下面的登录表单查看文章。这篇文章也可以购买。
文摘
我们的目标是描述患者的临床特征和治疗结果脊髓髓内转移(或弹性体)。没有报告的经验,这种罕见的癌症并发症。我们回顾了记录回顾从1980年到1993年确定组织学证实系统性的癌症患者,脊髓病的临床特征,tissue-proven或弹性体或异常的神经影像学研究结果一致或弹性体。我们确定了40个病人满足这些标准。在9个,或弹性体是癌症的最初表现。19病人肺初选(12)小细胞。21患者疼痛,35了显而易见的感觉丧失,37个弱点,25尿失禁在演讲。9名患者真正Brown-Sequard综合症和九人pseudo-Brown-Sequard综合症。症状诊断的平均持续时间是28天(范围3天至18个月)。13名患者脑转移之前,九有脑转移同时或弹性体,和一个后大脑转移或弹性体;11名伴有leptomeningeal转移。 Spinal magnetic resonance findings were abnormal in 30/30 patients, myelographic results were abnormal in 16/20, and eight had pathologic confirmation of ISCM. Thirty-five patients had radiotherapy and five had surgery; four were untreated or treated elsewhere. Median survival was 4 months for patients receiving radiotherapy and 2 months for patients not receiving radiotherapy. Eleven patients survived >6 months. Twenty-three were ambulatory at ISCM diagnosis, and 21 were ambulatory at latest follow-up. We conclude that ISCM as the initial presentation of malignancy is not rare, and hemicord syndromes occur frequently. Although long-term survival is poor, treatment preserves ambulation in most patients still ambulatory at diagnosis. Focal radiotherapy is indicated in most patients.
首页神经学1996;47:906 - 912
- 版权1996年Advanstar通信公司。
